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For nearly two decades, how kidney cancer becomes resistant to rapalog drugs has baffled the scientific community. Now a study by researchers at UT Southwestern Medical Centerâs Kidney Cancer Program sheds light
During a Case-Based Roundtable® event, Sumanta Kumar Pal, MD, discussed regimens for recurrent metastatic clear cell renal cell carcinoma including lenvatinib plus everolimus, belzutifan, and investigational cell therapy and bispecific agents in the second article of a 2-part series.
More research is needed to see whether levels of PD-1-expressing tumor macrophages may help identify patients who will respond better to immunotherapy.
The median progression-free survival with the combination was 19.83 months.
Abnormalities in the extracellular matrix (ECM) play important roles in the regulation and progression of clear cell renal cell carcinoma (ccRCC). The cysteine cathepsin is one of the major proteases involved in ECM remodeling and has been shown to be aberrantly expressed in multiple cancer ...
Patients with advanced renal cell carcinoma with previous exposure to lenvatinib derived modest benefit with tyrosine kinase inhibitors.
Kidney renal clear cell carcinoma (KIRC) is the most common histological type of renal cancer, enhancer RNA plays a significant role in tumor growth, however, it has been less studied in renal cancer. The aim of this study was to investigate the role of eRNA AC003092.1 in KIRC. Clinical and ...
DelveInsight s Renal Cell Carcinoma Pipeline Insight 2024 report provides comprehensive insights about 30 companies and 30 pipeline drugs in Renal Cell Carcinoma pipeline landscape It covers the pipeline drug profiles including clinical and nonclinical stage products It also covers ...
Benjamin L. Maughan, MD, PharmD, highlights ongoing research regarding the role of cytoreductive nephrectomy and targeted therapies in RCC.
Neil M. Iyengar, MD, focuses on the use of artificial intelligence in the oncology space.
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Articles from Kidney Cancer UK
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