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ACOX2 destabilizes the MRE11-RAD50-NBS1 complex and boosts anticancer immunity via the cGAS-STING pathway in clear cell renal cell carcinoma – Molecular Cancer

ACOX2 destabilizes the MRE11-RAD50-NBS1 complex and boosts anticancer immunity via the cGAS-STING pathway in clear cell renal cell carcinoma – Molecular Cancer

The rapid development of ICI-based immunotherapy has ushered in a promising era for clear cell renal cell carcinoma (ccRCC). However, durable clinical responses remain limited to a subset of patients. Therefore, identifying novel predictive biomarkers and developing effective combination ...
Development and evaluation of deep neural networks for the classification of subtypes of renal cell carcinoma from kidney histopathology images

Development and evaluation of deep neural networks for the classification of subtypes of renal cell carcinoma from kidney histopathology images

Renal cell carcinomas (RCCs) are the seventh most widespread histological cancer. Around 40% of patients die in RCC due to the disease development. Thus, this tumour is the most lethal malignant urological tumour. The histopathologic classification of RCC is vital for the prognosis, diagnosis, ...
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Articles from Kidney Cancer UK

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