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“We identified a myeloid mimicry pathway that can drive tumor hyper progression following immunotherapy in renal medullary carcinoma. Inhibiting this ...

Subcutaneous nivolumab was noninferior to intravenous nivolumab for the treatment of advanced or metastatic clear cell renal cell carcinoma (ccRCC), ...

Rare subtypes of renal cancers can be difficult to diagnose. Here, the authors use transcriptional analysis to show utility in aiding histological classification.

Kidney renal cell carcinoma (RCC) is a highly invasive malignancy, where early-stage diagnosis can significantly reduce treatment complexity and mortality risk. This study aims to enhance diagnostic precision through a novel model, RCC-ProbNet, capable of identifying and classifying RCC across ...

In recent years, the search for robust biomarkers to guide treatment and predict outcomes in cancer has taken on new urgency, especially in the context of clear cell renal cell carcinoma (ccRCC). This

For patients with renal cell carcinoma (RCC), receiving adjuvant durvalumab with tremelimumab after nephrectomy improves disease-free survival ...

ccRCC is an aggressive, heterogeneous tumor with a poor prognosis. Prognostic assessments need multi-modal data. Radiological images have limits, while pathological images offer micro-level details. Integrating these for ccRCC outcome prediction is important. Our study aimed to develop and ...

Assess the clinical effectiveness of robotic versus standard laparoscopic partial nephrectomy in treating solitary renal tumors. We retrospectively analyzed data from those who underwent laparoscopic (LPN, n = 28) or robot-assisted partial nephrectomy (RAPN, n = 16) at our institution between ...

STX16 has been studied in various cancers, where it is suggested to regulate tumor cell proliferation, migration, and invasion by affecting vesicle trafficking and signal transduction pathways. However, its specific role in clear cell renal cell carcinoma (ccRCC) remains unclear. This study ...

In patients with renal cell carcinoma, greater abdominal adiposity and lower skeletal mass are associated with aggressive pathology.
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Articles from Kidney Cancer UK
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