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TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3

TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3

Papillary renal cell carcinoma (pRCC) is a challenging renal cell carcinoma subtype with poor prognosis and limited treatment options due to the lack of reliable biomarkers. The tripartite motif (TRIM) protein family is involved in various cellular processes, including oncogenesis. Among ...
Frontiers | Case Report: Complete Response to Preoperative Ipilimumab and Nivolumab Combination Therapy in Advanced Papillary Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus and Multiple Metastases

Frontiers | Case Report: Complete Response to Preoperative Ipilimumab and Nivolumab Combination Therapy in Advanced Papillary Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus and Multiple Metastases

... Papillary Renal Cell Carcinoma with Inferior Vena Cava Tumor Thrombus and Multiple Metastases. Provisionally accepted. Chika Nagahisa ...
Comparison of partial nephrectomy and radical nephrectomy for cystic renal cell carcinoma: a SEER-based and retrospective study

Comparison of partial nephrectomy and radical nephrectomy for cystic renal cell carcinoma: a SEER-based and retrospective study

Renal cell carcinoma (RCC) is one of the most common tumors of the urinary system. Herein, we examined the epidemiology and prognostic factors of RCC and investigated the prognosis of partial nephrectomy (PN) compared to radical nephrectomy (RN) for T1b RCC over the past 20 years. We obtained ...
The prognostic role of key factors in renal cell carcinoma with bone metastases – BMC Musculoskeletal Disorders

The prognostic role of key factors in renal cell carcinoma with bone metastases – BMC Musculoskeletal Disorders

Objectives Our study aims to investigate the factors associated with survival in patients with skeletal metastases of renal cell carcinoma and to outline the principles of managing patients with skeletal metastases using a multidisciplinary approach. Materials and methods We retrospectively ...
Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids – Cell Death Discovery

Exercise-induced lactate suppresses ccRCC via CNDP2-mediated depletion of intracellular amino acids – Cell Death Discovery

Although epidemiological evidence has established a link between physical exercise and reduced risk and recurrence of multiple cancers, the association between physical exercise and cancer risk varies depending on the cancer site. Therefore, there is an urgent need to explore the molecular ...
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Articles from Kidney Cancer UK

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