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Kidney Cancer News elsewhere on the Web

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells

Primary cilia are present on renal tubules and are implicated to play a pivotal role in transducing signals during development; however, the oncogenic role of cilia in clear cell renal cell carcinoma (ccRCC) has not been examined. Here we show that VHL wild-type ccRCC cell lines have a high ...
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Articles from Kidney Cancer UK

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