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Renal cell carcinoma (RCC) is one of the most common tumors of the urinary system. Herein, we examined the epidemiology and prognostic factors of RCC and investigated the prognosis of partial nephrectomy (PN) compared to radical nephrectomy (RN) for T1b RCC over the past 20 years. We obtained ...

Five-year data from the phase 3 KEYNOTE-426 trial confirm the clinical benefits of front-line pembrolizumab plus axitinib in advanced ccRCC.

Rana R. McKay, MD, FASCO, discusses findings from the ARC-20 trial of casdatifan plus cabozantinib in pretreated clear cell renal cell carcinoma.

Objectives Our study aims to investigate the factors associated with survival in patients with skeletal metastases of renal cell carcinoma and to outline the principles of managing patients with skeletal metastases using a multidisciplinary approach. Materials and methods We retrospectively ...

A groundbreaking Phase 3 clinical trial, KEYNOTE-426, has delivered compelling evidence that a combination of pembrolizumab and axitinib significantly enhances long-term survival outcomes in patients

Although epidemiological evidence has established a link between physical exercise and reduced risk and recurrence of multiple cancers, the association between physical exercise and cancer risk varies depending on the cancer site. Therefore, there is an urgent need to explore the molecular ...

The investigational agent exhibited superior efficacy vs pembrolizumab in patients with lung cancer, suggesting potential efficacy in kidney cancer.

Current guidelines on treatment of metastatic renal cell carcinoma (mRCC) suggest an emerging role of local therapy (LT). Still there is a lack of data which patients may benefit from additional LT once medical treatment (MT) is initiated. We retrospectively aim to characterize LT in patients ...

Combining renal vaccines with immune therapy may better target tumor cells while limiting harm to healthy tissue, according to David A. Braun, MD, PhD.

KIM-1 is a biomarker in the blood that may help noninvasively detect kidney cancer, according to Wenxin (Vincent) Xu, MD.
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Articles from Kidney Cancer UK
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