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Casdatifan Monotherapy Shows Early Efficacy Signals and Tolerable Safety Profile in Pretreated ccRCC
Treatment with casdatifan was well tolerated and showed meaningful clinical activity in patients with previously treated ccRCC.
Renal cell carcinoma (RCC) is an aggressive malignancy originating from the renal parenchyma, often leading to high mortality due to local invasion and distant metastasis. MicroRNAs (miRNAs) play essential roles in RCC progression. Through miRNA sequencing, we identified significant ...
During a Case-Based Roundtable® event, Elizabeth M. Wulff-Burchfield, MD, and other participants discussed their experiences with the frontline combination regimens for advanced renal cell carcinoma.
An expert discusses using sequence therapies based on disease progression, patient factors, and resistance mechanisms. After a first-line tyrosine kinase inhibitor plus immune checkpoint inhibitor (TKI + ICI) regimen, preferred subsequent-line options include alternative TKIs, chemotherapy, ...
Urologic malignancies, including prostate, kidney, bladder, and testicular cancers, have historically presented significant therapeutic challenges, with conv...
A brief overview of the current RCC landscape was provided in the most recent Oncology Decoded podcast.
“What we hope overall is that this is a biological study that might inform therapeutic development for this disease,” says David A. Braun, MD, PhD.
Julie M. Vose, MD, MBA, discusses some of the lasting effects that the COVID-19 pandemic has had on the current state of cancer care.
Alan Tan, MD, discusses potential biomarkers that are being investigated to optimize treatment of patients with renal cell carcinoma.
Objective: To assess the feasibility of utilizing parameters derived from a multimodal apparent diffusion (MAD) model to distinguish between low-and high-gra...
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Articles from Kidney Cancer UK
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