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The FDA cleared ADC, ZW191, for difficult-to-treat cancers, immunotherapy showed varied efficacy in angiosarcomas, and the cabozantinib/nivolumab combination demonstrated promising results in RCC. We also cover FDA setbacks for botensilimab/balstilimab in mCRC, and the lackluster effects of ...

An emerging diagnostic model incorporating radiomic features from intratumoral and peritumoral regions exhibited a 29 percent higher AUC and 77 percent higher sensitivity rate than a clinical model for predicting the grading of clear cell renal cell carcinoma, according to recent research.

A phase 2 trial is assessing ubamatamab in patients with MUC16-expressing SMARCB1-deficient renal medullary carcinoma and epithelioid sarcoma.

Renal cell carcinoma (RCC) is considered a “metabolic disease” characterized by elevated glycolysis in patients with advanced RCC. Tyrosine kinase inhibitor (TKI) therapy is currently an important treatment option for advanced RCC, but drug resistance may develop in some patients. Combining ...

Worldwide, the incidence of renal cell carcinoma (RCC) is rising, accounting for approximately 2% of all cancer diagnoses and deaths. The etiology of RCC is still obscure. Here, we assessed the presence of HPyVs in paraffin-embedded tissue (FFPE) resected tissue from patients with RCC by using ...

Renal cell carcinoma (RCC) is responsible for 2% of all cancer diagnoses and mortality globally. 1 Individuals with a mutation in the von Hippel- ...

Analysis of 2 phase 1 trials compared gut biome diversity between standard of care with or without CBM588 in patients with metastatic renal cell carcinoma.

... renal cell carcinoma. 程帆, Chinese Medical Association Publishing House, 2002. The expression of P16 protein in childhood acute lymphoblastic ...

Renee Saliby, MD, MSc discusses the relationship between intermediate end points and overall survival in metastatic renal cell carcinoma.

The panel examines the key findings from abstract 4512 and evaluates its potential impact on the current treatment paradigm for renal cell carcinoma.
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Articles from Kidney Cancer UK
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